Skip to main content
| | | Screen Reader Access |   
   |   
  • Non-sulfated steroidal glycosides cistoindosides from marine old woman octopus Cistopus indicus attenuate pro-inflammatory lipoxygenase

    Two non-sulfated steroidal glycosides, cistoindosides A-B were isolated from organic extract of the marine ‘old woman octopus’ Cistopus indicus (family Octopodidae).The anti-inflammatory properties were corroborated by the promising antioxidant activities  of these steroid glycosides. Sizeably greater electronic properties, balanced hydrophobic-lipophilic properties  and comparatively lower steric factors were directly proportional to their bioactivities. Molecular simulation studies in the active sites of 5-lipoxygenase displaying lesser binding energies and inhibition constant (Ki) of cistoindoside B could be correlated with anti-inflammatory properties. Cistoindosides could be projected for their utilization as potential bioactive leads in functional food and pharmaceutical applications.

    Read More...

  • Mitogenomic profiling of Marcia recens (Holten, 1802): a step towards taxonomic resolution of India's Ashtamudi short-neck clam
  • Morphometry and biology of the Saddle grunt, Pomadasys maculatus, (Bloch,1793) recorded from the Southeast Arabian Sea
  • Fishery and reproductive biology of the spotted sardinella, Amblygaster sirm (Walbaum, 1972) exploited along the southern coast of India
  • De novo transcriptome for Chiloscyllium griseum, a long-tail carpet shark of the Indian waters
  • Energy efficiency and economics of small-scale fisheries (SSF) in India: A VIKOR based multicriteria decision-making model for sustainable fisheries management
  • Assessment of marine fish stocks within India’s Exclusive Economic Zone: Status report 2022
  • img
  • img
  • img
  • img
  • img
  • img
  • img

Search...