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  • Marine cuttlefish derived 2H benzochromenone, Pharachromenone as a dual inhibitor of pro inflammatory 5 lipoxygenase and cyclooxygenase2

    Cephalopod cuttlefish, Sepia pharaonis, has been considered as a commercially important resource, which is widely regarded as nutritious food in the southwest of Indian and Mediterranean coasts. Chemical analysis of the crude extract of S.Greater electronic parameters, lesser steric bulkiness, along with acceptable lipophilic-hydrophobic balance significantly contributed toward its promising anti-inflammatory activities.Pharachromenone could be developed as a functional food component against oxidative stress-related inflammatory disorders. pharaonis could result in the isolation of a 2H benzochromenone derivative, pharachromenone exhibiting potent antioxidant and anti-inflammatory properties. This study recognized the therapeutic potential of a marine cuttlefish-originated food constituent against inflammatory conditions, and could be anticipated as a high-value functional food lead to minimize oxidative stress-related inflammatory disorders.

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